OTC Over The Counter Medications (Viagra) (BUY)

In today's society, especially in the mouths of young people, there are often two words that are very shy, namely Viagra, a thing that Viagra can encounter as a man, which is still very mysterious for many people. In China in particular, not everyone is ready to discuss this topic, and knowledge about Viagra is very limited. How much does Viagra cost? In this article, the publisher of Pickup China will give you a detailed introduction. Viagra is actually a drug for sexual dysfunction. The more common Viagra in China is called Viagra, a drug imported from abroad. The appearance of the word also has its magic story. Although Viagra can improve people's sex lives, ordinary people are not recommended to take Viagra. The following is a detailed introduction for everyone.

The chemical name of "Viagra" is "Citric Acid Polyphenol", an oral medicine used to treat impotence (erectile dysfunction) in men. Because of its unique effectiveness, it has caused a worldwide sensation within a short time since its approval by the US Drug Administration (FDA) in March 1998. It is said to selectively control the activity of the "V-type phosphodiesterase" in the human body. A series of physiological and chemical reactions relax the smooth muscles of the cavernous body of the penis so that a large amount of blood can flow in, which clogs and swells the cavernous body, causing penile erection.

If you are concerned about oral medicines like Viagra, you can try the following Jingdong Hot Push Spray. The effect is very good and has no negative effects ↓

Viagra is not an aphrodisiac, it does not increase libido, it only works when libido is impulsive, and restores male erectile function under normal conditions, but only under normal conditions, not outside the normal range. What are the effects of Viagra? Viagra is an oral medicine, 50 mg per item. It is also very convenient to use, and the effectiveness may take 4-6 hours or continue until the climax.

Although the effects of Viagra are obvious, there are also negative effects. These side effects are mild and don't last too long. Some side effects only occur after taking a high dose.

3. The history of Viagra

Viagra first entered clinical research as a 5-phosphodiesterase inhibitor for the treatment of cardiovascular diseases. The researchers hope that sildenafil can relax the smooth cardiovascular muscles by releasing the biologically active substance nitric oxide to achieve the purpose of expanding blood vessels and alleviating cardiovascular diseases. However, clinical studies have shown that the effect of sildenafil on the cardiovascular system does not meet the expectations of the researchers. As a cardiovascular drug, the performance of sildenafil is disappointing and cannot become a successful therapeutic drug.

In April 1991, the clinical trial of sildenafil officially failed, but a side effect reported by the subject caught the researchers' attention. The researchers found that therapists were reluctant to dispense the remaining medication after receiving the test. After tracing, it was found that this drug has improved the patient's sex life.

In 1999 the word "ViagraHas been added to the Oxford Dictionary. At the same time, clinical studies confirmed cardiovascular safety.

In 2000, the study confirmed the safety of sildenafil in relation to blood pressure and the safety in combination with antihypertensive drugs.

In 2001 Viagra was approved for marketing in more than 100 countries worldwide with an average of 6 tablets per second.

In 2002, human clinical studies further confirmed that sildenafil had no effect on sperm function. The article was published in the British Journal of Clinical Pharmacology.

In 2003, 120 controlled studies confirmed that sildenafil did not increase the risk of myocardial infarction / cardiovascular death. The article was published in the International Journal of Clinical Practice.

In 2004, research confirmed that sildenafil improved self-esteem, self-esteem, relationship with sexual partners and overall patient quality of life by improving erections (SEAR and QoL).

In 2005 Viagra had over 750,000 prescriptions and over 23 million men

In 2006, the study further confirmed that Viagra helped men achieve Erectile Hardness 4 (the best erection hardness).

In 2007, a 4-year long-term study confirmed the long-term safety and long-term effectiveness of Viagra.

In 2008, research confirmed that erection hardness is an important treatment expectation for patients with ED.

In 2009, a color Doppler ultrasound study confirmed that treatment with Viagra 100 mg significantly improved penile blood flow.

In 2010, the meta-analysis further confirmed its safety (67 placebo-controlled double-blind studies).

In 2011, Sildenafil added more than 4,800 articles to the Pubmed database and more than 38 million men used Viagra

In 2012 Viagra 10 capsules were launched in China

Viagra launched new packaging in 2013

4. How much does Viagra cost?
Regarding the price of Viagra, this article introduces two types: one is the China-made Viagra called Baiyunshan Jinge and the other is Viagra from the United States. The prices are introduced as follows.

There are currently different types of packaging for Viagra. There are 1 pack, 5 packs and 10 packs. The corresponding prices are of course different. As long as you buy more, the price will of course go down. At present, the market price for 1 capsule sold on the market is 128 yuan, while the price for 5 capsules is about 495 yuan and the price for 10 capsules is even lower, only 965 yuan.

With a dosage unit of 50 mg / capsule, Jinge is divided into 5 different packaging specifications, such as: B. one pack, two packs, three packs, four packs and ten packs. Different packaging specifications and colors are used in different packaging markets collocation. The market price for 1 capsule is 48 yuan, the price for 2 capsules is about 89 yuan, the price for 3 capsules is 133 yuan, the price for 4 capsules is 178 yuan and the price for 10 capsules is 345 yuan.

Each is about 100 yuan. Pfizer's reports generally cost $ 2,000 a day to research and develop new drugs. Only Viagra is a drug. R&D investment exceeds $ 1 billion. Such a high investment in research and development must of course be paid for in the patient's pocket.

5. Instructions for using Viagra

1. Where can I buy Viagra?

Viagra drugs are currently available in hospital pharmacies and pharmacies. But in China, Viagra is a prescription drug and you need to show the prescription when you buy it. In order to get the best treatment effect and avoid dangerous situations for the first time, it is best to go to the hospital to find a specialist who will confirm the diagnosis and use it appropriately under the guidance of the doctor to avoid abuse and abuse .

With longer use and positive effect, you can buy it yourself in the pharmacy. It should be noted that some pharmacies recommend so-called "aphrodisiac" and health products to patients. These medicines are mostly mixed with western medicinal ingredients, and their safety is difficult to guarantee. Please do not buy and use at will.

2. What are the side effects of Viagra?

Longer erection: Men with urethritis can cause the penis to sit up for a long time after ingestion, damage the pudendal tissue and even increase impotence. If you have an erection that lasts longer than 4 hours, you need to see a doctor immediately.

Dizziness: There may be a sudden drop in blood pressure. If you take nitroglycerin and other medications at the same time, you will immediately feel dizzy or even weak.

Visual changes: 3% to 6% of patients experience color blindness and blurred vision after taking Viagra, and some may also have the illusion of seeing blue light. The symptoms may go away after 1 week of withdrawal. Drivers, pilots and retinal detachment patients should be used with caution.

Headache: 16% of the side effects are headache. The higher the dosage, the more severe the headache.

In addition, side effects such as hot flashes, indigestion, diarrhea, nasal congestion, urinary tract infections and rashes can occur.

3. Will Viagra be resistant if taken regularly?

Answer: Taking PDE5 inhibitors in a small dose over a long period of time can also improve the endothelial cells of the penile blood vessels and maintain the number of smooth muscle cells that can cure erectile dysfunction. According to the latest research and reports at home and abroad, drug resistance has not been found and many patients can still get good results after prolonged use.

4. What drugs can Viagra be used with?

(1) Carbamazepine, dexamethasone, rifampicin: the same use reduces the effectiveness.

Because rifalpine is a drug that increases the activity of CYP3A4, it can reduce the effectiveness of Viagra.

(2) Ketoconazole, clarithromycin, environmental bacteria, itraconazole and ritonavir: the combined use leads to poisoning.

Human metabolizing drugs cannot do without the help of enzymes, CYP3A4 is the most important enzyme in drug metabolism. Most drugs, including anti-Viagra drugs, are metabolized by CYP3A4. The above medicines can inhibit the activity of CYP3A4, and concomitant use of Viagra can increase the concentration of the former in the blood and increase the potential toxicity of the drug. It's not just drugs that have this effect. Certain drinks such as grapefruit juice can also inhibit the activity of CYP3A4. Patients who take Viagra should respect this.

(3) Nitroglycerin and other nitrate drugs (such as nitroglycerin) and α-blockers (such as doxazosin, prazosin, terazosin, tamsulosin, alfuzosin, etc.): The combined use lowers blood pressure and easily leads to accidents such as coma.

This is because "Viagra" has a vasodilator effect and nitroglycerin and prazosin also have a vasodilator effect. In combination, this effect is enhanced, which significantly lowers blood pressure and increases the risk of heart disease or stroke.

5. Why does Viagra have no effect after taking it?

Viagra is not a traditional "aphrodisiac", it does not cause a direct erection of the penis, but prevents the premature loss of the penis vasodilator (cyclic guanosine phosphate) produced by the brain during sexual arousal. Therefore, this medicine alone does not cause an erection and it must be stimulated by the brain. The so-called "Viagra" can take on this role if there is more than one heart.

In particular, there are three factors for the effectiveness of "Viagra".

(1) The drug dose is also very important

"Viagra" usually has 3 doses: 25 mg, 50 mg and 100 mg. If you are using it for the first time, you will normally take a dose of 50 mg. If the effect is not good, you can increase the dose to 100 mg. However, it is best to take a dose of 25 mg for the elderly over 65 years of age. Currently, most of the dosage forms of "Viagra" sold in China are 100 mg per tablet. You can use a sharp knife to split them in two or four.

(2) Pay attention to the details of taking medication

Before taking the drug, avoid fullness, eat cold and greasy food, and do not drink alcohol. The best time to take the drug is at night, and it is best to take the drug on an empty stomach 1 hour before sex.

(3) medication time

After taking the drug for 1 hour, it is effective if it is supplemented by sexual stimulation (note: do not perform any sexual stimulation within 1 hour after taking the drug, because the drug effect has not yet peaked at this point).

Typically, the effective rate of Viagra is around 80%, which means that more than 20% of people still use it to be invalid. If you followed the previous two points and still have no effect, it is recommended to go to the hospital to check the specific cause of impotence. Since "Viagra" also "faints", "Viagra" is also helpless with impotence, which is caused by low sex hormones and penile insufficiency.

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